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Also known as myophosphorylase deficiency.
McArdle disease is a rare metabolic disorder which causes muscle pain in everyday activities and exercise. If activity is prolonged despite the pain then muscle damage ensues with the risk of muscle breakdown and kidney failure.
Symptoms are usually apparent during the first decade of life but many people do not manage to obtain a diagnosis until the third or fourth decade. Later in life some people with McArdle disease experience fixed muscle weakness, possibly from cumulative muscle damage. It is important for those with McArdle disease to take regular aerobic exercise such as walking and avoid anaerobic activities such as lifting heavy weights.
The Coordinator for Type V is Andrew Wakelin, who has McArdle's himself. (This is a voluntary role.) Everyone in the UK diagnosed with McArdle's should register with Andrew to be kept up-to-date with developments. Contact him via the Contact us page, or telephone him on 01597 860686.
About the disease
Exercise and McArdle Disease
Association for Glycogen Storage Disease (UK) LimitedRegistered Charity No 1132271