HARRISON FORD IN GSD FILM
Extraordinary Measures starring Harrison Ford, based on the book "The Cure" it tells the story of John Crowley and his part in funding the development of an enzyme-replacement therapy for people with Pompe Disease. Two of John's children suffer from Pompe (GSD Type II). UK release 26th February.

 

MCARDLE HANDBOOK PROJECT
Thanks to the Vodafone Foundation Kathryn Wright is preparing a Handbook for people with McArdle's. More details here.

 


 

HARRISON FORD IN GSD FILM
Extraordinary Measures starring Harrison Ford, based on the book "The Cure" it tells the story of John Crowley and his part in funding the development of an enzyme-replacement therapy for people with Pompe Disease. Two of John's children suffer from Pompe (GSD Type II). UK release 26th February.

 

MCARDLE HANDBOOK PROJECT
Thanks to the Vodafone Foundation Kathryn Wright is preparing a Handbook for people with McArdle's. More details here.

 

Glycogen Storage Disease Type V

Also known as McArdle disease or myophosphorylase deficiency.

McArdle disease is a rare metabolic disorder which causes muscle pain in everyday activities and exercise. If activity is prolonged despite the pain then muscle damage ensues with the risk of muscle breakdown and kidney failure.

Symptoms are usually apparent during the first decade of life but many people do not manage to obtain a diagnosis until the third or fourth decade. Later in life some people with McArdle disease experience fixed muscle weakness, possibly from cumulative muscle damage. It is important for those with McArdle disease to take regular gentle aerobic exercise and avoid anaerobic activities such as lifting heavy weights.

 

Type V summary
Symptoms Muscle pain on everyday activity and exercise.
Fatigue. Fixed contractures with rhabdomyolysis.
Secondary symptoms Raised urate level. Possible muscle wasting.
Treatment No specific treatment. Maintain healthy diet,
control weight, take gentle aerobic exercise.
Outlook Good with gentle aerobic exercise and
avoidance of anaerobic activity.

Glycogen Storage Disease Type V

Also known as McArdle disease or myophosphorylase deficiency.

McArdle disease is a rare metabolic disorder which causes muscle pain in everyday activities and exercise. If activity is prolonged despite the pain then muscle damage ensues with the risk of muscle breakdown and kidney failure.

Symptoms are usually apparent during the first decade of life but many people do not manage to obtain a diagnosis until the third or fourth decade. Later in life some people with McArdle disease experience fixed muscle weakness, possibly from cumulative muscle damage. It is important for those with McArdle disease to take regular gentle aerobic exercise and avoid anaerobic activities such as lifting heavy weights.

 

Type V summary
Symptoms Muscle pain on everyday activity and exercise.
Fatigue. Fixed contractures with rhabdomyolysis.
Secondary symptoms Raised urate level. Possible muscle wasting.
Treatment No specific treatment. Maintain healthy diet,
control weight, take gentle aerobic exercise.
Outlook Good with gentle aerobic exercise and
avoidance of anaerobic activity.